Ngokohlaziyo lwakamuva lwe-meta, i-positron emission tomography/computed tomography (PET/CT) kanye ne-multi-parameter magnetic resonance imaging (mpMRI) inikeza amazinga afanayo okutholwa ekuxilongeni umdlavuza wendlala yesinye (PCa) ukuphindeka.
Abacwaningi bathola ukuthi i-prostate ethize i-membrane antigen (PSMA) PET/CT inenani eliphelele lokutholwa lamaphesenti angama-69 wokuphindaphinda komdlavuza wendlala yesinye, uma kuqhathaniswa namaphesenti angama-70 we-mpMRI.
"Ngenxa [yokuphindaphinda kwe-biochemical], zombili izindlela ziyasebenza. Imiphumela yethu ibonisa ukuthi awukho umehluko ophawulekayo ku-DR (izinga lokutholwa) phakathi kwezindlela ezimbili zokucabanga, futhi i-mpMRI ibiza kakhulu ngenkathi igcina i-DR efanayo, "ubhale umbhali ohlangene wocwaningo u-L. Xu, osebenzisana neSikole Sezokwelapha. Hunan University of Traditional Chinese Medicine, Hunan, China kanye nozakwabo.
Ngokuphindaphindiwe kwe-PCa yendawo, abalobi bocwaningo baqaphele ukuthi i-DR On mpMRI yayiyi-10% ephakeme (62% vs. 52%). Abacwaningi baphinde bathola ukuthi i-PSMA PET/CT ibonise ukuthuthukiswa kwe-18% ku-DR Lapho kuhlolwa i-lymph node metastasis (50% kanye ne-32%, ngokulandelana). Kodwa-ke, akukho okutholakele okwakubalulekile ngokwezibalo, kusho ababhali bocwaningo.
Abacwaningi bakholelwa ukuthi ukuzwela okuphezulu nokucacile kungase kunikeze i-PSMA PET / CT inzuzo ku-PCa staging kanye nokubona izilonda ezincane, kodwa futhi bavume ukuthi ukutholakala kwendlela kuyinkinga. I-MRI yamapharamitha amaningi ingase ibe usizo ekuhloleni ukuphindaphinda kwendawo kanye ne-PCa ebalulekile emtholampilo, kodwa abalobi bocwaningo bayavuma ukuthi i-interrobserver heterogeneity ingase ibe yinkinga nge-mpMRI.
Kodwa-ke, imiphumela yonke yokuhlaziywa kwe-meta iphakamisa ukuthi zombili izindlela zinendima ekuxilongeni i-PCa BCR, futhi zikhomba izifundo ezizokwenzeka esikhathini esizayo ezinganikeza ukucaca okukhulu kulokhu.
U-Xu kanye nozakwabo bagcizelele umthelela omkhulu wemiphumela yocwaningo ekusebenzeni komtholampilo. Babonisa ukuthi amandla okuxilonga afanayo we-PSMA PET / CT kanye ne-mpMRI abonisa ukuphumelela kwazo zombili izindlela ekutholeni i-BCR kuziguli ze-PCa. Kodwa-ke, bagcizelele isidingo socwaningo olwengeziwe ukuze kuhlolwe ukufinyeleleka, ukufinyeleleka, kanye nempumelelo yezindleko zalezi zindlela zokuthwebula izithombe.
Lapho bexoxa ngemikhawulo yocwaningo, ababhali bavuma ukuthi usayizi omncane wesampula weziguli ezingama-290 wawuwumphumela wokugxila kwabo ekuhlaziyeni izifundo zokuqhathanisa zokuthola i-BCR ngaphakathi kwamaqembu esiguli afanayo. Baphinde baphakamisa ukuthi kungenzeka kube nokuchema emiphumeleni ngenxa yezinqubo ezahlukene zokucabanga nezici zesiguli kuzo zonke izifundo eziyisithupha abazibuyekezile.
—————————————————————————————————————————————————————————————————————————————————————
Ngokuthuthuka kobuchwepheshe bezithombe zezokwelapha, kuphuma izinkampani eziningi ezingahlinzeka ngemikhiqizo yokuthwebula izithombe, njengama-injection namasirinji.I-LnkMedubuchwepheshe bezokwelapha bungenye yazo. Sihlinzeka ngephothifoliyo egcwele yemikhiqizo yokuhlola eyisiza:I-CT injector eyodwa,CT umjovo wekhanda kabili,Umjovo we-MRIfuthiI-DSA high pressure injector. Basebenza kahle ngemikhiqizo ehlukahlukene yesithwebuli se-CT/MRI njenge-GE, Philips, Siemens. Ngaphandle komjovo, siphinde sinikeze isirinji kanye neshubhu esetshenziswayo yezinhlobo ezahlukene zomjovo ohlanganisa i-Medrad/Bayer, iMallincrodt/Guerbet, iNemoto, iMedtron, i-Ulrich.
Okulandelayo amandla ethu ayisisekelo: izikhathi zokulethwa okusheshayo; Qedela iziqu zesitifiketi, iminyaka eminingi yesipiliyoni sokuthekelisa, inqubo yokuhlola ikhwalithi ephelele, imikhiqizo esebenza ngokugcwele, siyawamukela ngemfudumalo umbuzo wakho.
Isikhathi sokuthumela: Apr-18-2024
