Yiziphi Intuthuko Yamuva Ezithombeni Zezokwelapha?

Kusukela ekuqaleni kwawo ngawo-1960 kuya kuma-1980, i-Magnetic Resonance Imaging (MRI), i-computerized tomography (CT) scans, kanye ne-positron emission tomography (PET) scans ziye zathuthuka kakhulu. Lawa mathuluzi okuthwebula izithombe zezokwelapha angangenisi umthelela aqhubeke nokukhula ngokuhlanganiswa kobuhlakani bokwenziwa (AI), amasu athuthukisiwe okuqoqwa kwedatha eluhlaza, kanye nokuhlaziywa kwezibalo okune-multi-parametric, konke okunomthelela ekuqondeni okuthuthukisiwe kanye nokuhlaziywa kwezinhlelo zethu zangaphakathi.

Ukuthuthukiswa kwe-PET kanye ne-CT scans

Ukuskena kwe-PET okujwayelekile ngokuvamile kudinga phakathi kwemizuzu engama-45 nehora ukuze kuqedwe futhi kungaveza izithombe ezihlukile zokukhula kwesimila ebuchosheni, emaphashini, emlonyeni wesibeletho, nakwezinye izindawo zomzimba. Intuthuko eqhubekayo ithuthukise ukusebenza kahle kwale ndlela, ifaka isofthiwe yokulungisa ukufiphala kokunyakaza futhi ivumela ukuhlolwa kwe-algorithmic ukubikezela indawo yesisindo ngaphakathi kwezicubu ezihambayo.

Ukufiphaza kokunyakaza kwenzeka lapho ingxenye eqondiwe inyakaza ngesikhathi sokuthwebula isithombe se-PET scan, okwenza kube nzima kakhulu ukuhlola nokuhlaziya isisindo noma izicubu. Ukuze kuncishiswe ukunyakaza ngesikhathi sokuthwebula i-PET, ochwepheshe bezempilo basebenzisa ukutholwa okuvalwe ngesango, bahlukanise umjikelezo wokuskena ube “amabhokisi” amaningi. Ngokuhlukanisa inqubo yokuskena ibe amabhokisi angu-8-10, uhlelo lungabikezela indawo yesisindo esiqondiwe ngesikhathi noma endaweni ethile, ngokusekelwe kulokho okuthandwa ngumsebenzisi. Lesi sibikezelo senziwa ngokubikezela indawo yesisindo ngaphakathi kwamabhokisi ngamanye omjikelezo. Inqubo yokuthwebula nge-PET evalwe ngesango inciphisa ngempumelelo ukufiphaza kokunyakaza okungokwemvelo kudivayisi, okuholela ekuthuthukisweni kokuhlushwa komsebenzi/inani lokuvuselela elijwayelekile (i-SUV). Lapho idatha ye-PET ihambisana nedatha ye-CT, yonke inqubo yaziwa ngokuthi ukuskena kwe-4D CT.

Noma kunjalo, kunomkhawulo obonakalayo ohambisana nale nqubo. Ukusebenzisa izindlela ezivikelwe ukuze kutholakale izithombe kuholela ekukhuleni komsindo ohlobene ngenxa yokutholwa kwedatha enkulu kakhulu. Amasu amaningana okubhekana nale nkinga afaka phakathi i-Q-freeze, i-Oncofreeze, kanye nesikhathi sokundiza (ToF).

Indlela ukufiphala kwesithombe okulungiswa ngayo ngaphakathi kwe-PET kanye ne-CT scans

Ukulungiswa kwesithombe okusekelwe ku-Q-freeze, kusetshenziswa ukutholwa kwesango, kuhilela ukuqoqwa nokubhaliswa kwazo zonke izithombe ezikhiqizwe. Lokhu kubhaliswa kwenzeka ngaphakathi kwesikhala sesithombe, ukuqoqa nokwakha kabusha yonke idatha eluhlaza etholwe ku-PET scan ukuze kukhiqizwe isithombe sokugcina esinomsindo oncishisiwe kanye nokufiphala.

I-OncoFreeze, inqubo yesofthiwe yokubukisa, ihambisana ne-Q-freeze ngezindlela ezithile, yize ihlukile iyonke. Ukulungiswa kokunyakaza kwenziwa esikhaleni se-sinogram (isikhala sedatha eluhlaza). Ngemva kokuthola isithombe sokuqala, izithombe ezilandelayo ezifiphalisiwe ziboniswa phambili futhi ziqhathaniswa nedatha ebikezelwe yebhentshi lomsebenzi wokuhlinzwa kanye nezilinganiso ze-sinogram ze-backproject. Lokhu kuholela esithombeni sokugcina esibuyekeziwe ngokusekelwe esithombeni sokulungiswa esilungisiwe.

Ukuthwebula ama-waveform okuphefumula ngesikhathi sokuskena kwe-PET kuhlanganiswe nokuskena kwe-CT kungaholela ekhwalithini yesithombe ethuthukisiwe. Ukuqondanisa okuthuthukisiwe kungabonakaliswa ngokuvumelanisa ama-waveform okuskena kwe-PET, indlela evamile, nama-waveform okuskena kwe-CT, indlela esanda kuthuthukiswa.

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Njengoba sonke sazi, intuthuko yemboni yezithombe zezokwelapha ayihlukaniseki ekuthuthukisweni kochungechunge lwemishini yezokwelapha - ama-injector agent injector kanye nezinto ezisetshenziswayo ezisekelayo - ezisetshenziswa kabanzi kulo mkhakha. EShayina, edume ngemboni yayo yokukhiqiza, kunabakhiqizi abaningi abadumile ekhaya nakwamanye amazwe ngokukhiqiza imishini yezithombe zezokwelapha, okuhlanganisaI-LnkMedKusukela yasungulwa, i-LnkMed ibilokhu igxile emkhakheni wama-injectors anamandla aphezulu okucindezela. Ithimba lobunjiniyela le-LnkMed liholwa yi-Ph.D. elinolwazi olungaphezu kweminyaka eyishumi futhi lihileleke kakhulu ocwaningweni nasekuthuthukisweni. Ngaphansi kwesiqondiso sakhe, i-Umjovo wekhanda elilodwa le-CT, Umjovo wekhanda eliphindwe kabili we-CT, Umjovo we-MRI contrast agent, futhiI-Angiography high-pressure contrast agent injector injectorzenzelwe lezi zici: umzimba oqinile futhi ohlangene, isikhombimsebenzisi sokusebenza esilula nesihlakaniphile, imisebenzi ephelele, ukuphepha okuphezulu, kanye nomklamo ohlala isikhathi eside. Singaphinde sinikeze amasirinji namashubhu ahambisana nalawo mabhrendi adumile e-CT, MRI, DSA injectors Ngenxa yesimo sabo sengqondo esiqotho kanye namandla ochwepheshe, bonke abasebenzi be-LnkMed bakumema ngobuqotho ukuthi nize nizohlola izimakethe ezengeziwe ndawonye.